Philip Bourne

Philip Bourne
Born
Philip Eric Bourne

1953 (1953)
Died (aged 72)
Charlottesville, Virginia, US
Alma materFlinders University (PhD)
Known for
Spouse
Roma Chalupa
​
(m. 1983)​
Children2
Awards
Scientific career
FieldsData science
Computational biology
Scholarly communication[5]
Bioinformatics
Institutions
ThesisCrystal structure analyses :
metal complexes of biological interest and the stereochemistry of substituted phonylbicyclooctanes
 (1979)
Notable studentsWerner G. Krebs
Websitedatascience.virginia.edu/people/phil-bourne

Philip Eric Bourne (1953 – 8 March 2026) was an Australian bioinformatician,[9] non-fiction writer[6] and businessman.[8] He was the Stephenson Chair of Data Science, director of the School of Data Science, Professor of Biomedical Engineering[10] and the first associate director for data science at the National Institutes of Health, where his projects include managing the Big Data to Knowledge initiative, and formerly associate vice chancellor at UCSD.[11] He contributed to textbooks and was a strong supporter of open-access literature and software. His diverse interests spanned structural biology, medical informatics, information technology, structural bioinformatics, scholarly communication and pharmaceutical science.[9] His papers are highly cited with an h-index above 80. With over 100,000 citations, he was one of the University of Virginia's most cited researchers.[12][13][5][14]

Early life and education

Bourne was born in 1953.[15] He trained as a physical chemist in the mid to late 1970s and obtained his PhD in 1979 at Flinders University in Adelaide, South Australia.[15]

Career and research

After his PhD, Bourne moved to the University of Sheffield in the UK to do postdoctoral research during 1979–1981,[16] followed by a move to Columbia University, New York, in 1981. In 1995 he moved to University of California, San Diego, where he was a Professor in the Department of Pharmacology. In 2014, he moved to NIH to become its associate director for Data Science. In January 2017, it was announced that he had accepted a position as director of University of Virginia's Data Science Institute.[17]

He was known for writing the book Unix for VMS Users (1990)[6] and for being co-developer of the Combinatorial Extension algorithm for the three-dimensional alignment of protein structures,[18] together with I. Shindyalov (1998). In 1999 he became co-director of the Protein Data Bank.[19] He was president of the ISCB (2002–2003).[20] He became a fellow of the American Medical Informatics Association in 2002.[21] In 2005, he became founding Editor in Chief of PLOS Computational Biology. In 2007 he co-founded SciVee.[8] Bourne was an editor of the popular Ten Simple Rules series of editorials published in PLOS Computational Biology journal.[22] He served as the Associate Vice Chancellor for Innovation and Industrial Alliances[11] and a professor of pharmacology at the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California, San Diego (UCSD).[23][24] He was an advisor to the Hypothes.is project[25] and associate director for data science at the National Institutes of Health where his projects included managing the Big Data to Knowledge initiative.[26][27]

Personal life and death

Bourne married Roma Chalupa in 1983 and they had two children, Scott and Melanie.[14] His interests included motorcycles,[28][29] flying and hiking. Bourne died on 8 March 2026, at the age of 72, following a protracted battle with mesothelioma.[14]

Publications

Bourne authored numerous scientific articles and book chapters and was editor of the Structural Bioinformatics textbook.[30][31] and Pharmacy Informatics.[32] Other publications[5] included:

  • Structural Bioinformatics 1st edition[30]
  • Structural Bioinformatics 2nd edition[31]
  • Pharmacy Informatics[32]
  • Unix for Vms Users[6]
  • Bourne, Philip E. (1997-01-01). A Cookbook for Serving the Internet for UNIX. Prentice Hall. ISBN 9780135199923.
  • Hart, David L.; Bourne, Philip E. (1998-08-12). Mac OS 8 Web Server Cookbook (1st ed.). Prentice Hall PTR. ISBN 9780135200162.
  • Bourne, Philip E. (2000-01-01). Underground Guide Unix. Prentice Hall. ISBN 9780131844582.
  • Berman, H. M.; Westbrook, J.; Feng, Z.; Gilliland, G.; Bhat, T. N.; Weissig, H.; Shindyalov, I. N.; Bourne, P. E. (2000-01-01). "The Protein Data Bank". Nucleic Acids Research. 28 (1): 235–242. doi:10.1093/nar/28.1.235. ISSN 0305-1048. PMC 102472. PMID 10592235.

Awards and honours

Bourne was elected a Fellow of the AAAS under Pharmaceutical Sciences in 2011[1] and a fellow of the International Society for Computational Biology (ISCB) in 2011.[2] In 2010 he won Microsoft's Jim Gray e-Science award[3] and in 2009 won that year's Benjamin Franklin Award.[4][33]

References

  1. ^ a b "Dr. Phil Bourne elected AAAS Fellow under Pharmaceutical Sciences". Pharmacy.ucsd.edu. Retrieved 2011-02-27.
  2. ^ a b "ISCB fellows". Archived from the original on 2015-03-28. Retrieved 2011-08-15.
  3. ^ a b "Philip E. Bourne wins Microsoft's 2010 Jim Gray eScience Award". Eurekalert.org. 2010-10-18. Retrieved 2011-02-27.
  4. ^ a b "Benjamin Franklin Award". Bioinformatics.org. Retrieved 2011-02-27.
  5. ^ a b c Philip Bourne publications indexed by Google Scholar
  6. ^ a b c d Bourne, Phil E (1990). Unix for VMS Users. Digital Press Newton, MA, USA. ISBN 1-55558-034-3.
  7. ^ Berman, H. M.; Westbrook, J.; Feng, Z.; Gilliland, G.; Bhat, T.; Weissig, H.; Shindyalov, I.; Bourne, P. (2000). "The Protein Data Bank". Nucleic Acids Research. 28 (1): 235–242. doi:10.1093/nar/28.1.235. PMC 102472. PMID 10592235.
  8. ^ a b c Fink, JL; Bourne, PE (2007). "Reinventing Scholarly Communication for the Electronic Age". CTWatch Quarterly. 3 (3).
  9. ^ a b Philip Bourne publications indexed by the Scopus bibliographic database. (subscription required)
  10. ^ "Philip e. Bourne". 6 July 2017.
  11. ^ a b "Appointment of Associate Vice Chancellor − Innovation and Industry Alliances (Part-Time Administrative)" (PDF). Archived from the original (PDF) on 2012-07-31. Retrieved 2012-07-02.
  12. ^ Webpage at the University of Virginia
  13. ^ Bourne's old website
  14. ^ a b c Mather, Mike (9 March 2026). "In memoriam: Philip Bourne, founding dean of the School of Data Science". news.virginia.edu. Retrieved 10 March 2026.
  15. ^ a b Bourne, Philip Eric (1979). Crystal structure analyses : metal complexes of biological interest and the stereochemistry of substituted phonylbicyclooctanes (PhD thesis). Flinders University. OCLC 708090572.
  16. ^ Clegg, G. A.; Stansfield, R. F. D.; Bourne, P. E.; Harrison, P. M. (1980). "Helix packing and subunit conformation in horse spleen apoferritin". Nature. 288 (5788): 298–300. Bibcode:1980Natur.288..298C. doi:10.1038/288298a0. PMID 7432529. S2CID 4335735.
  17. ^ "UVA Names NIH Researcher as New Director of Data Science Institute". 11 January 2017.
  18. ^ Shindyalov, I. N.; Bourne, P. E. (1998). "Protein structure alignment by incremental combinatorial extension (CE) of the optimal path". Protein Engineering Design and Selection. 11 (9): 739–747. doi:10.1093/protein/11.9.739. PMID 9796821.
  19. ^ Berman, H. M.; Westbrook, J.; Feng, Z.; Gilliland, G.; Bhat, T.; Weissig, H.; Shindyalov, I.; Bourne, P. (2000). "The Protein Data Bank". Nucleic Acids Research. 28 (1): 235–242. doi:10.1093/nar/28.1.235. PMC 102472. PMID 10592235.
  20. ^ "ISCB — Past Presidents". Archived from the original on August 28, 2015. Retrieved September 3, 2015.
  21. ^ Greenes, R. A.; Madsen, E.; Miller, R. A. (2003). "American College of Medical Informatics Fellows and International Associates, 2002". Journal of the American Medical Informatics Association. 10 (3): 281–286. doi:10.1197/jamia.M1326. PMC 400512.
  22. ^ Ten Simple Rules
  23. ^ http://www.sdsc.edu/pb/ The Bourne lab web page
  24. ^ http://www.sdsc.edu/~bourne/CV.pdf Philip E. Bourne Ph.D. CV
  25. ^ Hypothes.is official website
  26. ^ "NIH Names Dr. Philip E. Bourne First Associate Director for Data Science".
  27. ^ Margolis, R.; Derr, L.; Dunn, M.; Huerta, M.; Larkin, J.; Sheehan, J.; Guyer, M.; Green, E. D. (2014). "The National Institutes of Health's Big Data to Knowledge (BD2K) initiative: capitalizing on biomedical big data". Journal of the American Medical Informatics Association. 21 (6): 957–8. doi:10.1136/amiajnl-2014-002974. ISSN 1067-5027. PMC 4215061. PMID 25008006.
  28. ^ OFL | Philip Bourne | Travel Blog
  29. ^ McKenzie, Bryan (7 August 2025). "Born to be mild? UVA deans take their machines on the road". news.virginia.edu. Retrieved 10 March 2026.
  30. ^ a b Bourne, Philip E.; Weissig, Helga (2003). Structural Bioinformatics. John Wiley & Sons.
  31. ^ a b Gu, Jenny; Bourne, Philip E. (March 2009). Structural Bioinformatics (2nd ed.). Wiley-Blackwell. ISBN 978-0-470-18105-8.
  32. ^ a b Anderson, Philip O.; Bourne, Philip E. (December 2009). Pharmacy Informatics. CRC Press. ISBN 978-1-4200-7175-7.
  33. ^ "The Bourne Commendation: Open Access Evangelist Wins 2009 Benjamin Franklin Award". Bio-itworld.com. Retrieved 2011-02-27.
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