Jesse Roth

Jesse Roth (August 5, 1934 – March 11, 2026) was an American physician and endocrinologist at The Feinstein Institute for Medical Research.

Roth received his BA in 1955 from Columbia University, his MD in 1959 from Albert Einstein College of Medicine.

Roth completed a residency in internal medicine at Barnes-Jewish Hospital (Washington University School of Medicine, St. Louis) in 1961, and a fellowship in endocrinology at Bronx Veterans Administration Medical Center in 1963.^[1][2][3][4] Beginning with his fellowship work with Solomon Berson and Rosalyn Yalow, Jesse Roth's research career focused on insulin action. He pioneered the concept of cell surface receptors.^[5] His laboratory at the National Institutes of Health elucidated much of what we know of the structure of the insulin receptor and intracellular mechanisms of insulin action.

Roth died on March 11, 2026, at the age of 91.^[6]

Roth was a fellow of the American College of Physicians and was a recipient of the 1980 Gairdner Foundation International Award^[7][8] and in 1982 he received the American Diabetes Association's Banting Medal for Scientific Achievement.^[9]